Surya Prasad
BP Koirala Institue of Health Sciences, Nepal
Title: A randomized controlled trial of loading dose only versus standard dose magnesium sulfate seizure prophylaxis in severe pre-eclamptic women
Biography
Biography: Surya Prasad
Abstract
Magnesium sulfate is the drug of choice for prevention of seizures in the pre-eclamptic woman. There is no agreement in the published randomized trials regarding the optimal time to initiate magnesium sulfate, the dose to use (both loading and maintenance) as well as the duration of therapy. The objective of this study is to determine whether magnesium sulfate (MgSO4) prophylaxis is needed for up to 24 hours postpartum in all patients with severe pre-eclampsia for the prevention of seizure. The primary outcome measures were occurrence of seizure in each group. Secondary outcome measures were maternal and neonatal outcome.